Mofarotene

SKU: orb1819158

Description

Mofarotene (Ro-40-8757) is a synthetic retinoid that activates retinoic acid receptors (RARs), modulating gene expression to inhibit proliferation and promote differentiation in susceptible cells. It has demonstrated antitumor activity in various cancer cell lines and in vivo models, supporting its research in oncology and respiratory diseases.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 125533-88-2
• MW: 433.63
• Purity: 99.96% (May vary between batches)
• Formula: C₂₉H₃₉NO₂
• SMILES: CC1(C)C=2C(C(C)(C)CC1)=CC=C(\C(=C\C3=CC=C(OCCN4CCOCC4)C=C3)\C)C2
• Target: Caspase,Retinoid Receptor,ROS,Reactive Oxygen Species,Apoptosis
• Solubility: DMSO:2.17 mg/mL (5 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Mofarotene, Retinoid Receptor, RetinoidReceptor, Ro 40-8757, Ro-40-8757, RAR

Compound Identifiers

PubChem CID

5467732