MNS

SKU: orb1300630

Description

MNS is a multi-kinase inhibitor that potently targets p97, Syk, and Src with respective IC50 values of 1.7 μM, 2.5 μM, and 29.3 μM. This small molecule is a useful research tool for investigating signaling pathways in immunology and oncology, with applications in both cellular and biochemical assays.

Research Area

Cardiovascular Research, Immunology & Inflammation, Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 1485-00-3
• MW: 193.16
• Purity: 98.53% (May vary between batches)
• Formula: C₉H₇NO₄
• SMILES: [O-][N+](=O)\C=C\c1ccc2OCOc2c1
• Target: Syk,NOD-like Receptor (NLR),Integrin,p97,Src
• Solubility: 10% DMSO+90% Corn Oil:1.5 mg/mL (7.77 mM);Ethanol:1 mg/mL (5.18 mM);DMSO:19.3 mg/mL (99.92 mM)

Bioactivity

• Target IC50:
  p97:1.7 μM|Syk:2.5 μM|Src:29.3 μM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

derivative, beta-nitrostyrene, aggregation, activation, GPIIb/IIIa, MNS, p97, NSC170724, NSC-170724, NSC 170724, inhibit, Inhibitor, platelet, Syk, Src, Spleen tyrosine kinase, thrombin

Compound Identifiers

PubChem CID

672296