mNLS-CPP-WSTF TFA

SKU: orb3180405

Description

mNLS-CPP-WSTFTFA is the trifluoroacetate salt form of mNLS-CPP-WSTF, a cell-penetrating peptide based on the mouse WSTF sequence with a nuclear localization signal (NLS). This compound significantly inhibits the interaction between GABARAP and WSTF, as well as WSTF degradation and the expression of inflammatory genes. It effectively alleviates chronic inflammation, liver fibrosis, and cartilage damage in mouse models of metabolic dysfunction-associated steatotic hepatitis (MASH) and osteoarthritis (OA). mNLS-CPP-WSTF holds research potential for chronic inflammatory diseases such as MASH and OA.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• Target: GABA Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

GABA Receptor