Mn(Ⅲ) Protoporphyrin IX Chloride

SKU: orb1980136

Description

Mn(III) Protoporphyrin IX Chloride is a manganese-chelated porphyrin complex investigated as a contrast agent for magnetic resonance imaging (MRI). It serves as a potent relaxation enhancer in preclinical research for both in vitro studies and in vivo imaging applications.

Research Area

Immunology & Inflammation, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 120389-54-0
• MW: 651.03
• Purity: 97.62% (May vary between batches)
• Formula: C₃₄H₃₂ClMnN₄O₄
• SMILES: O=C(CCC1=C(C)C2=[N]3C1=CC4=C(CCC([O-])=O)C(C)=C5C=C6C(C=C)=C(C)C(C=C7C(C=C)=C(C)C8=C2)=[N]6[Mn+3]3([N-]78)([N-]54)[Cl-])[O-].[H+].[H+]
• Target: Others,ROS
• Solubility: 0.1 M Na2CO3:4 mg/mL (6.14 mM);2 M NaOH:8 mg/mL (12.29 mM)

Bioactivity

• In Vitro:
  Mn(Ⅲ) Protoporphyrin IX Chloride is a metalloporphyrin. At a concentration of 10 μM, it up-regulates the mRNA expression of the genes encoding δ-aminolevulinic acid synthase and heme oxygenase (HO), which are responsible for catalyzing the rate-limiting steps of heme biosynthesis and degradation, respectively, in chicken embryo hepatocytes.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Manganese(III) Protoporphyrin IX Chloride, Manganese(Ⅲ) Protoporphyrin IX Chloride

Quick Database Links

Gene Symbol

Others,ROS