MMP-9-IN-14

SKU: orb3210073

Description

MMP-9-IN-14 is an MMP-9 inhibitor (IC50= 34.46 μM) that induces G1 phase cell cycle arrest and caspase-dependent apoptosis in cancer cells. It promotes the accumulation of phosphorylated γH2AX and inhibits the migration and invasion of cancer cells by downregulating the expression of MMP-2, MMP-9, and hTERT. In animal models, MMP-9-IN-14 suppresses tumor growth and angiogenic spreading. It is applicable in research on lung adenocarcinoma, cervical cancer, colorectal cancer, and other cancers.

Key Properties

• Target: Caspase,MMP,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Caspase,MMP,Apoptosis