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MMP-9-IN-12

SKU: orb3136671

Description

MMP-9-IN-12 is an inhibitor of matrix metalloproteinase-9 (MMP-9) with an IC50 value of 6.57 μM. It demonstrates an IC50 of 1.54 μM in HCT-116 cells and can induce apoptosis, reactive oxygen species (ROS) generation, and mitochondrial depolarization. Additionally, MMP-9-IN-12 inhibits cell migration and disrupts cell cycle progression, making it useful for colorectal cancer (CRC) research.

Research Area

Cancer Biology; Musculoskeletal & Connective Tissue Research, Cell Biology, Immunology & Inflammation, Protein Biochemistry

Images & Validation

Key Properties

TargetROS,Apoptosis,MMP

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information