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Catalog Number | orb1981214 |
---|---|
Category | Small Molecules |
Description | MMI-0100, a cell-permeant peptide inhibitor of mitogen-activated protein kinase activated protein kinase II (MK2), effectively reduces intimal hyperplasia ex vivo and in vivo. It specifically suppresses IL-6 expression while not affecting IL-8 expression and mitigates fibrotic processes, including vein graft disease [1]. |
Purity | 98.00% |
MW | 2283.64 |
Biological Activity | MMI-0100, a cell-permeant peptide inhibitor of mitogen-activated protein kinase activated protein kinase II (MK2), effectively reduces intimal hyperplasia ex vivo and in vivo. It specifically suppresses IL-6 expression while not affecting IL-8 expression and mitigates fibrotic processes, including vein graft disease [1]. |
CAS Number | 1039342-24-9 |
Formula | C98H171N37O26 |
SMILES | [C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=C(O)C=C1)N)=O)C)=O)CCCNC(=N)N)=O)C)=O)C)=O)C)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)C)=O)CCCNC(=N)N)=O)C)=O)CCCCN)=O)C)=O)CC(C)C)=O)C)=O)CCCNC(=N)N)=O)(C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)C)=O)C)=O)[C@H](C)C)=O)=O)CC(C)C)=O)CCC(N)=O |
Storage | -20°C |
Note | For research use only |
> 95% by hplc | |
2283.64 Da | |
H-Tyr-Ala-Arg-Ala-Ala-Ala-Arg-Gln-Ala-Arg-Ala-Lys-Ala-Leu-Ala-Arg-Gln-Leu-Gly-Val-Ala-Ala-OH |