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MMI-0100

SKU: orb1981214

Description

MMI-0100, a cell-permeant peptide inhibitor of mitogen-activated protein kinase activated protein kinase II (MK2), effectively reduces intimal hyperplasia ex vivo and in vivo. It specifically suppresses IL-6 expression while not affecting IL-8 expression and mitigates fibrotic processes, including vein graft disease.

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Key Properties

CAS Number1039342-24-9
MW2283.64
FormulaC98H171N37O26
SMILES[C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=C(O)C=C1)N)=O)C)=O)CCCNC(=N)N)=O)C)=O)C)=O)C)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)C)=O)CCCNC(=N)N)=O)C)=O)CCCCN)=O)C)=O)CC(C)C)=O)C)=O)CCCNC(=N)N)=O)(C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)C)=O)C)=O)[C@H](C)C)=O)=O)CC(C)C)=O)CCC(N)=O

Storage & Handling

Storage-20°C
DisclaimerFor research use only

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MMI-0100 (orb1981214)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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