MM-401 TFA

SKU: orb1982162

Description

MM-401 (TFA) is a potent and selective inhibitor of the MLL1 methyltransferase, disrupting the MLL1-WDR5 interaction with an IC50 of 0.32 µM. This small molecule induces cell cycle arrest, apoptosis, and differentiation in vitro, making it a valuable chemical probe for studying MLL-rearranged leukemias.

Research Area

Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation

Key Properties

• CAS Number: 1442106-11-7
• MW: 700.75
• Formula: C₃₁H₄₇F₃N₈O₇
• SMILES: C(C(O)=O)(F)(F)F.O=C1[C@H](NC(=O)[C@H](CC)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@](NC(C(C)C)=O)(C)CCCCN1)C2=CC=CC=C2
• Target: Histone Methyltransferase,Apoptosis,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

137662115