MLS-573151

SKU: orb1306093

Description

MLS-573151 is a potent and selective small molecule inhibitor of the GTPase Cdc42, with an EC50 of 2 μM. It functions by competitively blocking GTP binding, showing no activity against related GTPases like Rac1 or RhoA. This compound is a valuable research tool for investigating Cdc42's role in cell migration, cytoskeletal dynamics, and oncogenesis in both cellular and animal models.

Research Area

Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 10179-57-4
• MW: 377.46
• Purity: 99.64% (May vary between batches)
• Formula: C₂₁H₁₉N₃O₂S
• SMILES: NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1ccccc1)c1ccccc1
• Target: CDK,Ras
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.3 mM);DMSO:30 mg/mL (79.48 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cdc42, MLS 000573151, MLS 573151, MLS573151, MLS-573151, MLS000573151, MLS-000573151, inhibit, Inhibitor, GTPase, granulocytes, Ras

Compound Identifiers

PubChem CID

2837695