MLS-0053105

SKU: orb2802382

Description

MLS-0053105 is a chloromaleimide-based selective BFL-1 inhibitor with an IC50 of 0.4 µM. It exhibits over tenfold selectivity against Bcl-W, Bcl-2, and Bcl-XL and is inactive against Bcl-B and Mcl-1. This tool compound is used in vitro to study BFL-1's role in apoptosis and cancer cell survival.

Research Area

Cell Biology, Metabolism Research

Key Properties

• CAS Number: 370572-36-4
• MW: 374.65
• Formula: C₁₅H₁₄Cl₃N₃O₂
• SMILES: O=C1C(Cl)=C(C(=O)N1C2=CC=C(Cl)C(Cl)=C2)N3CCN(C)CC3
• Target: FXR,Bcl-2 Family

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

1180676