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MLN-3897

SKU: orb1699923

Description

MLN-3897 is a potent, orally bioavailable CCR1 antagonist with a Ki of 2.3 nM. It blocks MIP-1α binding, inhibits downstream Akt signaling, and suppresses multiple myeloma cell survival and proliferation in vitro, making it a useful research tool for studying inflammation and oncology pathways.

Research Area

Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1010731-97-1
MW519.03
Purity98.62%
FormulaC30H31ClN2O4
SMILESC(CCN1CC(C)(C)[C@](O)(CC1)C2=CC=C(Cl)C=C2)=C3C=4C(OCC=5C3=CC=CN5)=CC=C(C(O)=O)C4
TargetCCR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Protocol Information

MLN-3897 (orb1699923)

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