MLK3-IN-1

SKU: orb2945601

Description

MLK3-IN-1 (Compound 37) is a potent and selective mixed-lineage kinase 3 (MLK3) inhibitor (IC50 <1 nM) with excellent metabolic stability in liver microsomes. It also inhibits FAK at a much higher IC50 of 15.5 µM. This tool compound is used in biochemical and cellular research to investigate MLK3 signaling pathways in cancer and inflammatory diseases.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• MW: 490.422
• Formula: C₂₀H₁₆F₆N₄O₂S
• SMILES: CS(=O)(=O)C1=CC=CC(=C1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC=C(C=C3)C(F)(F)F
• Target: MLK,FAK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172676994