ML327

SKU: orb1225829

Description

ML327 is a small molecule that restores E-cadherin expression through regulation of E-cadherin transcription, displays an In-Cell Western EC50 of 1.0 uM; is inactive (>30 uM) against all know epigenetic targets (HDACs, MMPs, Sirtuins, etc.) that increase E-cadherin expression, and clean in a Ricerca ancillary pharmacology panel; possesses favorable physiochemical properties, an excellent dystrophia myotonica protein kinase (DMPK) profile.

Key Properties

• CAS Number: 1883510-31-3
• MW: 366.377
• Purity: >98% (HPLC)
• Formula: C₁₉H₁₈N₄O₄
• SMILES: C1C=CNC(=O)C=1C(=O)NCCCNC(=O)C1=NOC(C2=CC=CC=C2)=C1
• Target: Cadherin
• Solubility: DMSO: 32 mg/mL （ < 1 mg/ml refers to the product slightly soluble or insoluble )

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ML 327

Quick Database Links

Gene Symbol

Cadherin