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ML303

SKU: orb1218681

Description

ML303 is an antagonist of pyrazolopyridine influenza virus nonstructural protein 1 (NS1) (IC90 : 155 nM).

Images & Validation

Key Properties

CAS Number1638211-04-7
MW399.37
Purity>98% (HPLC)
FormulaC21H16F3N3O2
SMILESOC1=CC=C(C2=CC=NC3=C2C(C)=NN3C4=CC=C(C(F)(F)F)C=C4)C=C1OC
TargetInfluenza Virus
SolubilityDMSO:10 mM

Bioactivity

In Vitro
ML303 (20 μM, 6 h) treatment restore IFN-β mRNA levels in MDCK cells. Western blot analysis. Cell line: MDCK cells infected with A/PR/8/34, at a MOI of 2, for 6 hours. Concentration: 20 μM. Incubation time: 6 hours. Result: Restored IFN-β mRNA levels in MDCK cells.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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    C21H16F3N3O2

    1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 1 ml x 10 mM (in DMSO)
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Protocol Information

Available Sizes

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200 mg
500 mg
5 mg
$ 450.00
10 mg
$ 670.00
25 mg
$ 1,070.00
50 mg
$ 1,520.00
100 mg
$ 2,080.00