ML192

SKU: orb1696045

Description

ML192 (CID1434953) is a selective GPR55 antagonist that potently inhibits β-arrestin recruitment, ERK1/2 phosphorylation, and PKCβII translocation. This compound is a valuable research tool for investigating GPR55 signaling in metabolic disorders, neuropathic pain, and cancer, both in vitro and in vivo.

Research Area

Epigenetics & Chromatin, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 460331-61-7
• MW: 382.48
• Purity: 99.79% (May vary between batches)
• Formula: C₂₀H₂₂N₄O₂S
• SMILES: Cc1nc(N2CCN(CC2)C(=O)c2ccco2)c2c3CCCCc3sc2n1
• Target: Cannabinoid Receptor,PKC,ERK,Arrestin,GPCR
• Solubility: DMSO:22.5 mg/mL (58.83 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.23 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ML 192, ML192, ML-192, GPR, GPR55, CannabinoidReceptor, Cannabinoid Receptor, CID 1434953, CID1434953, CID-1434953

Compound Identifiers

PubChem CID

1434953