ML-93

SKU: orb3173642

Description

ML-93 is an orally active SAE inhibitor with an IC50 value of 0.4 μM. It effectively inhibits the SUMOylation pathway in HCT116 cells and demonstrates potent antitumor activity in HCT116 colorectal cancer xenograft models. ML-93 is applicable in colorectal cancer research.

Research Area

Protein Biochemistry

Key Properties

• CAS Number: 1858275-91-8
• MW: 579.08
• Formula: C₂₅H₂₇ClN₄O₆S₂
• SMILES: CC1=C([C@H]2C=3C(CCO2)=CC=C(Cl)C3)C=C(C(=O)C=4C(N[C@@H]5C[C@H](COS(N)(=O)=O)[C@@H](O)C5)=NC=NC4)S1
• Target: E1/E2/E3 Enzyme

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

E1/E2/E3 Enzyme