ML-345

SKU: orb1694302

Description

Insulin-degrading enzyme (IDE) is a zinc-metallopeptidase crucial for insulin clearance and implicated in diabetes, Alzheimer's disease, and viral infection. ML-345 is a selective small-molecule inhibitor of IDE, targeting Cys819 with an EC50 of 188 nM and offering 10-fold selectivity, making it a valuable tool for studying IDE function in metabolic and neurological research.

Research Area

Protein Biochemistry

Key Properties

• CAS Number: 1632125-79-1
• MW: 479.55
• Purity: 99.21% (May vary between batches)
• Formula: C₂₁H₂₂FN₃O₅S₂
• SMILES: O=C1C2=CC(F)=CC=C2SN1C3=CC(=CC=C3N4CCOCC4)S(=O)(=O)N5CCOCC5
• Target: MMP

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

57390068