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Catalog Number | orb1307522 |
---|---|
Category | Small Molecules |
Description | ML-323 |
CAS Number | 1572414-83-5 |
Purity | 99.96% |
MW | 384.48 |
SMILES | C(C)(C)C1=C(C=CC=C1)C=2N=C(NCC3=CC=C(C=C3)N4C=CN=N4)C(C)=CN2 |
Formula | C23H24N6 |
Biological Activity | ML323 is a reversible and effective USP1-UAF1 inhibitor in a Ub-Rho assay (IC50: 76 nM) and in orthogonal gel-based assays using K63-linked diubiquitin (di-Ub) (IC50: 174 nM 820 nM)and monoubiquitinated PCNA (Ub-PCNA) (IC50: 820 nM) as substrates, respectively. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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