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ML-241

SKU: orb1226488

Description

ML241 is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM); blocks degradation of p97-dependent proteasome substrate with an IC50 of 3.5 uM; induces caspases 3 and 7 and potently blocks proliferation in HCT15 and SW403 cells.

Images & Validation

Key Properties

CAS Number1346528-06-0
MW372.46
Purity>98% (HPLC)
FormulaC23H24N4O
SMILESC1CCC2=C(C1)C(=NC(=N2)N3CCOC4=CC=CC=C43)NCC5=CC=CC=C5
Targetp97
Solubility10 mM in DMSO

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

ML 241 | ML241

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Protocol Information

ML-241 (orb1226488)

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Available Sizes

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100 mg
200 mg
500 mg
5 mg
$ 130.00
10 mg
$ 190.00
25 mg
$ 390.00
50 mg
$ 630.00