MKLP2-IN-1

SKU: orb2944560

Description

MKLP2-IN-1 (compound 12a) is an orally bioavailable small molecule inhibitor of the mitotic kinesin MKLP2. It potently inhibits MKLP2 ATPase activity in vitro and has demonstrated efficacy in suppressing tumor growth in a Calu-6 mouse xenograft model, supporting its use in cancer research.

Research Area

Signal Transduction

Key Properties

• CAS Number: 2929345-46-8
• MW: 468.318
• Formula: C₂₃H₁₉BrFN₃O₂
• SMILES: O=C1N(C=2C=CC=CC2C(Br)=C(C3=NN=C(O3)C4CC4)C1)CC5=CC=C(C(F)=C5)C
• Target: Kinesin

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172551558