MK-8033 hydrochloride

SKU: orb1709111

Description

MK-8033 hydrochloride is a potent, orally bioavailable dual c-Met/Ron kinase inhibitor with IC50 values of 1 nM and 7 nM, respectively. It preferentially binds the activated kinase conformation and has demonstrated research utility in models of breast cancer, bladder cancer, and non-small cell lung cancer (NSCLC) in both in vitro and in vivo studies.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1283000-43-0
• MW: 507.99
• Formula: C₂₅H₂₂ClN₅O₃S
• SMILES: Cl.Cn1cc(cn1)-c1cnc2ccc3ccc(CS(=O)(=O)NCc4ccccn4)cc3c(=O)c2c1
• Target: c-Met/HGFR,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

51030992