MK-8033 hydrochloride

SKU: orb1709111

Description

MK-8033 hydrochloride is a potent, orally bioavailable dual c-Met/Ron kinase inhibitor with IC50 values of 1 nM and 7 nM, respectively. It preferentially binds the activated kinase conformation and has demonstrated research utility in models of breast cancer, bladder cancer, and non-small cell lung cancer (NSCLC) in both in vitro and in vivo studies.

Research Area

Signal Transduction

Images & Validation

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Key Properties

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CAS Number	1283000-43-0
MW	507.99
Formula	C₂₅H₂₂ClN₅O₃S
SMILES	Cl.Cn1cc(cn1)-c1cnc2ccc3ccc(CS(=O)(=O)NCc4ccccn4)cc3c(=O)c2c1
Target	c-Met/HGFR,Others

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

51030992 ↗

Key Properties

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No computed properties available.

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