MK-4688

SKU: orb1691581

Description

MK-4688 is a potent and selective small molecule inhibitor that disrupts the HDM2-p53 protein-protein interaction. It is utilized in cancer research to reactivate p53 tumor suppressor pathways, with applications in both in vitro biochemical assays and in vivo xenograft studies.

Research Area

Cell Biology

Key Properties

• CAS Number: 1616428-79-5
• MW: 550.06
• Formula: C₂₈H₃₂ClN₇O₃
• SMILES: [H][C@@]12CCC[C@@]1([H])N(CCO2)c1nc2cc(nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1)-c1noc(=O)[nH]1 |wU:5.6,28.32,wD:1.0,31.36,(-.16,3.07,;,1.54,;-1.46,2.02,;-2.37,.77,;-1.46,-.48,;;-.16,-1.53,;1.33,-.77,;2.67,,;2.67,1.54,;1.33,2.31,;1.33,-2.31,;.09,-3.22,;.56,-4.68,;-.21,-6.01,;.56,-7.35,;2.1,-7.35,;2.87,-6.01,;4.41,-6.01,;5.18,-4.68,;6.72,-4.68,;7.49,-6.01,;6.72,-7.35,;7.49,-8.68,;5.18,-7.35,;2.1,-4.68,;2.58,-3.22,;4.04,-2.74,;4.36,-1.23,;3.22,-.2,;3.54,1.3,;5,1.78,;5.32,3.29,;6.15,.75,;5.83,-.76,;-.21,-8.68,;-1.74,-8.84,;-2.06,-10.35,;-.72,-11.12,;-.56,-12.65,;.42,-10.09,)|
• Target: Others,MDM-2/p53

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

136216281