MJN228

SKU: orb1699945

Description

MJN228 is a small molecule inhibitor of nucleobindin-1 (NUCB1), a lipid-binding protein. It effectively blocks AEA-DA probe labeling of endogenous NUCB1 in Neuro2a cells and serves as a useful research tool for investigating metabolic disorders in both cellular and animal models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 459168-97-9
• MW: 364.4
• Purity: 98.42% (May vary between batches)
• Formula: C₂₀H₂₀N₄O₃
• SMILES: O=C(N1CCN(CC1)C)C2=C(C3=CC=CC=C3)C4=C(C=CC([N+]([O-])=O)=C4)N2
• Target: Others,Liposome
• Solubility: DMSO:20 mg/mL (54.88 mM)

Bioactivity

• In Vitro:
  25 μM MJN228 significantly reduced lipid probe labeling of NUCB1 in Neuro2a cells. MJN228 interfered with multiple intracellular lipid metabolic pathways.
  Read more...

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

MJN 228, MJN228, MJN-228

Compound Identifiers

PubChem CID

22660592