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Mizoribine 5'-monophosphate

SKU: orb3175144

Description

Mizoribine 5'-monophosphate is the active metabolite of Mizoribine. It acts as an inhibitor of inosine-5’-monophosphate dehydrogenase (IMPDH), with inhibition constants (Ki) of 3.3, 72, and 157 nM for Trypanosoma brucei, Bacillus subtilis, and marine Bacillus species IMPDH, respectively. Mizoribine 5'-monophosphate is utilized in antitrypanosomal and immunosuppressive research.

Images & Validation

Key Properties

CAS Number62025-48-3
MW339.2
FormulaC9H14N3O9P
SMILESOC=1N(C=NC1C(N)=O)[C@@H]2O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]2O
TargetParasite,Dehydrogenase,Drug Metabolite

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information