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MitoBloCK-1

SKU: orb3174022

Description

MitoBloCK-1 is an inhibitor that obstructs the import of substrates reliant on the TIM22 pathway. It acts by preventing substrates from binding to the tim9/10 complex, thereby inhibiting their transport and preventing them from reaching the TIM22 translocase. MitoBloCK-1 impedes the mitochondrial import of TIM22 substrate proteins. Additionally, it hampers the transport of carrier proteins, such as ADP/ATP and phosphate carriers, and also inhibits the translocation of another carrier protein, PiC, along with the outer membrane protein Tom40.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number373370-73-1
MW368.25
FormulaC14H14BrN3O2S
SMILESS=C(N)NN=CC=1C(O)=C(Br)C=C2OC3=C(C21)CCCC3
TargetMitochondrial Metabolism

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information