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MIM1

SKU: orb1309422

Description

MIM1 is a selective small molecule inhibitor of the anti-apoptotic protein Mcl-1. It is a valuable research tool for studying apoptosis mechanisms and has been utilized in both in vitro and in vivo models to investigate cancers dependent on Mcl-1 for survival.

Research Area

Cell Biology

Images & Validation

Key Properties

CAS Number509102-00-5
MW347.43
Purity99.84% (May vary between batches)
FormulaC17H21N3O3S
SMILESCc1cs\c(=N\C2CCCCC2)n1\N=C\c1ccc(O)c(O)c1O
TargetBcl-2 Family
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.76 mM);DMSO:50 mg/mL (143.91 mM)

Bioactivity

In Vitro
MIM-1 specifically targets the BH3 binding groove of Mcl-1, inducing apoptosis in a Bak-dependent manner.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Bcl-2 Family, Inhibitor of Mcl 1, Inhibitor of Mcl1, Inhibitor of Mcl-1, Mcl-1, Inhibitor, inhibit, MIM 1, MIM1, MIM-1

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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1 mg
$ 80.00
2 mg
$ 90.00
5 mg
$ 120.00
1 ml x 10 mM (in DMSO)
$ 120.00
10 mg
$ 170.00