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Miglustat

SKU: orb1217697

Description

Miglustat is an alkylated product of imino sugar deoxynojirimycin.It is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1).

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number72599-27-0
MW219.28
Purity>98% (HPLC)
FormulaC10H21NO4
SMILESO[C@H]1[C@H](O)[C@@H](CO)N(CCCC)C[C@@H]1O
TargetOthers
SolubilityDMSO:10 mM

Bioactivity

In Vivo
Animal model: NPC1 / mice. Dosage: 0.2 mg/kg. Administration: Oral administration; once. Result: Was able to rescue synaptic plasticity deficits, to restore ERKs activation and to counteract hyperexcitability.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

N-Butyldeoxynojirimycin | NB-DNJ | OGT918

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Miglustat (orb1217697)

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% DMSO +
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Available Sizes

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200 mg
500 mg
5 mg
$ 140.00
10 mg
$ 190.00
25 mg
$ 330.00
50 mg
$ 530.00
100 mg
$ 750.00