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Midodrine hydrochloride
Catalog Number: orb1308122
| Catalog Number | orb1308122 |
|---|---|
| Category | Small Molecules |
| Description | Midodrine hydrochloride |
| CAS Number | 3092-17-9 |
| Purity | 99.79% |
| MW | 290.74 |
| SMILES | Cl.COc1cc(C(O)CNC(=O)CN)c(OC)cc1 |
| Formula | C12H19ClN2O4 |
| Biological Activity | Midodrine is converted to its active metabolite, desglymidodrine by deglycination reaction. Desglymidodrine selectively binds to and activates alpha-1-adrenergic receptors of the arteriolar and venous vasculature. This causes smooth muscle contraction and leads to an elevation of blood pressure. Desglymidodrine diffuses poorly across the blood-brain barrier and is therefore not associated with effects on the central nervous system. Midodrine hydrochloride (Pro-Amatine) is the hydrochloride salt form of midodrine, a direct-acting prodrug and sympathomimetic agent with antihypotensive properties. |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
