MID-1

SKU: orb1298643

Description

MID-1 is a small molecule inhibitor that disrupts the MG53-IRS-1 interaction. By blocking this interaction, it prevents MG53-mediated ubiquitination and degradation of IRS-1, thereby enhancing insulin signaling and glucose uptake in skeletal muscle cells. This compound is a valuable research tool for studying insulin resistance and metabolic disorders in both cellular and animal models.

Research Area

Signal Transduction

Key Properties

• CAS Number: 312608-54-1
• MW: 293.3
• Purity: 99.61% (May vary between batches)
• Formula: C₁₂H₁₁N₃O₄S
• SMILES: CCOc1ccc(cc1)C(=O)Nc1ncc(s1)[N+]([O-])=O
• Target: IGF-1R
• Solubility: DMSO:4.5 mg/mL (15.34 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

glucose, IGF1R, insulin, Insulin Receptor, Inhibitor, inhibit, IRS-1, MID 1, MID1, MID-1, MG53, MG53-IRS-1, degradation, association, ubiquitination

Compound Identifiers

PubChem CID

2858708