MI-888 free base

SKU: orb1738457

Description

MI-888 is a highly potent and orally bioavailable MDM2 inhibitor (Ki = 0.44 nM) demonstrating rapid and complete tumor regression in xenograft models. It is a premier research tool for studying p53-mediated pathways in oncology, applicable in both in vitro biochemical assays and in vivo efficacy studies.

Research Area

Cell Biology

Key Properties

• CAS Number: 1303607-59-1
• MW: 548.48
• Formula: C₂₈H₃₂Cl₂FN₃O₃
• SMILES: C(C(C)(C)C)[C@H]1[C@@]2([C@H]([C@H](C(N[C@H]3C[C@@](C)(O)C3)=O)N1)C4=C(F)C(Cl)=CC=C4)C=5C(NC2=O)=CC(Cl)=CC5
• Target: Others,MDM-2/p53

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

53477213