MI-1061 TFA

SKU: orb1983376

Description

MI-1061 TFA is a potent, orally bioavailable MDM2-p53 interaction inhibitor with an IC50 of 4.4 nM. It demonstrates robust p53 activation and apoptosis induction in vitro and shows significant in vivo anti-tumor efficacy in SJSA-1 xenograft mouse models.

Research Area

Cell Biology, Immunology & Inflammation, Protein Biochemistry

Key Properties

• CAS Number: 1410737-35-7
• MW: 696.47
• Formula: C₃₂H₂₇Cl₂F₄N₃O₆
• SMILES: C(C(O)=O)(F)(F)F.O=C1[C@@]2(C3(N[C@@H](C(NC4=CC=C(C(O)=O)C=C4)=O)[C@@H]2C5=C(F)C(Cl)=CC=C5)CCCCC3)C=6C(N1)=CC(Cl)=CC6
• Target: Others,MDM-2/p53,Apoptosis,E1/E2/E3 Enzyme

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

155981982