MG-277

SKU: orb1992781

Description

MG-277 is a molecular glue degrader derived from a PROTAC scaffold. It effectively suppresses tumor cell proliferation independently of p53 status, making it a valuable tool for studying targeted protein degradation in cancer research, both in vitro and in vivo.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Key Properties

• MW: 774.71
• Formula: C₄₁H₄₂Cl₂FN₅O₅
• SMILES: O=C(NCCCCCC1=CC=CC2=C1CN(C2=O)C(C(N3)=O)CCC3=O)[C@@H]4NC5(CCCCC5)[C@@]6(C(NC7=C6C=CC(Cl)=C7)=O)[C@H]4C8=CC=CC(Cl)=C8F
• Target: PROTACs|||Mdm2

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

139600332