MF-592

SKU: orb1737970

Description

MF-592 is a potent and selective EP4 receptor antagonist with nanomolar in vitro activity, including inhibition of TNFα release in human whole blood. It exhibits excellent oral pharmacokinetics and demonstrated significant in vivo efficacy in a rat model of chronic arthritis, supporting its potential for inflammatory disease research.

Research Area

Immunology & Inflammation, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1064195-48-7
• MW: 682.61
• Formula: C₃₄H₃₃Cl₂N₃O₆S
• SMILES: O(CC)C1=C2C(=C(OCC)C=3C1=CC=CC3)CN(C2=O)C4=C(C)C=C(CC5(NC(NS(=O)(=O)C6=C(Cl)C=CC=C6Cl)=O)CC5)C=C4
• Target: Others,Prostaglandin Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

25018911