METTL1-WDR4-IN-2

SKU: orb2565793

Description

METTL1-WDR4-IN-2 (compound 6) is a selective inhibitor of the METTL1-WDR4 methyltransferase complex with an IC50 of 41 µM. It exhibits significant selectivity over METTL3-METTL14 and modest selectivity against METTL16. This tool compound is used in vitro to investigate the role of m7G tRNA modification in cancer and stem cell biology.

Research Area

Epigenetics & Chromatin, Signal Transduction

Key Properties

• CAS Number: 2919742-07-5
• MW: 509.53
• Formula: C₂₄H₂₃N₅O₆S
• SMILES: O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](CSCC4=CC(=CC(C(O)=O)=C4)C5=CC=C(O)C=C5)[C@H]1O
• Target: DNA Methyltransferase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

170459228