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Methylprodnisolone Sodium Succinate

SKU: orb1225555

Description

A water-soluble ester of METHYLPREDNISOLONE used for cardiac, allergic, and hypoxic emergencies.

Images & Validation

Key Properties

CAS Number2375-03-3
MW496.53
Purity>98% (HPLC)
FormulaC26H33N3O6
SMILESO=C([O-])CCC(OCC([C@@](O)(CC1)[C@](C[C@H](O)[C@@H]2[C@@]3(C)C=C4)(C)[C@@H]1[C@@H]2C[C@H](C)C3=CC4=O)=O)=O.[Na+]
TargetGlucagon Receptor
SolubilitySoluble in DMSO

Bioactivity

In Vivo
Animal model: Male C57/BL mouse (6-8 weeks old, 20-23 g) injected with collagenase. Dosage: 30 mg/kg. Administration: ip; at 2, 24 and 48 h after ICH. Result: Significantly reduced permeability of the BBB and brain oedema and upregulated expression of ZO-1 and Occludin.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Methylprednisolone sodium succinate | U 9088 | U-9088 | U9088

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Protocol Information

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10 mg
$ 80.00
25 mg
$ 130.00
50 mg
$ 210.00
100 mg
$ 310.00
200 mg
$ 440.00
500 mg
$ 740.00