Methyldopa

SKU: orb1310547

Description

Methyldopa (MK-351) is a psychoactive antihypertensive agent that acts as a selective α2-adrenergic receptor agonist. It is widely used in cardiovascular research to study central sympathetic nervous system modulation in both in vivo models of hypertension and in vitro receptor binding assays.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 555-30-6
• MW: 211.21
• Purity: 99.89% (May vary between batches)
• Formula: C₁₀H₁₃NO₄
• SMILES: C([C@](C(O)=O)(C)N)C1=CC(O)=C(O)C=C1
• Target: Endogenous Metabolite,Dopamine Receptor,Adrenergic Receptor
• Solubility: DMSO:60 mg/mL (284.08 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (9.47 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

prodrug, response, inhibit, L-(-)-α-Methyldopa, L-α-Methyldopa, metabolized, Methyldopa, MK351, MK-351, MK 351, Inhibitor, hyperglycemic, L-alpha-Methyldopa, L-a-Methyldopa, Dopamine Receptor, DopamineReceptor, DOPA decarboxylase, Beta Receptor, AdrenergicReceptor, Adrenergic Receptor, antihyoertensive

Compound Identifiers

PubChem CID

38853