Methyl (Z)-1-acetyl-3-(ethoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate

SKU: orb3218229

Description

Methyl (Z)-1-acetyl-3-(ethoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate is a synthetic impurity or intermediate of the anti-pulmonary fibrosis drug Nintedanib. Nintedanib is an orally active multi-target tyrosine kinase inhibitor (TKI) that exerts anti-fibrotic effects by inhibiting receptor kinases such as VEGFR, PDGFR, and FGFR.

Key Properties

• CAS Number: 1027407-75-5
• MW: 365.38
• Formula: C₂₁H₁₉NO₅
• SMILES: C(\OCC)(=C\1/C=2C(N(C(C)=O)C1=O)=CC(C(OC)=O)=CC2)/C3=CC=CC=C3
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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