Methyl jasmonate

SKU: orb3054572

Description

Methyl jasmonate is a phytohormone involved in plant defenses under stress conditions. Methyl jasmonate can improve antioxidant properties of blueberry leaf extracts (mainly anthocyanins), and decrease the viability and migration capacity of AGS cells. Anticarcinogenic activity.

Key Properties

• CAS Number: 1211-29-6
• MW: 224.3
• Purity: >98% (HPLC)
• Formula: C₁₃H₂₀O₃
• Solubility: DMSO : 100 mg/mL (445.83 mM; ultraphonic; )

Bioactivity

• In Vitro:
  Methyl jasmonate-treated blueberry leaf extraction (10-3200 μg/mL; 1 hour) can decrease cell viability of AGS cells with increasing dose. Methyl jasmonate-treated blueberry leaf extraction (10-3200 μg/mL) can significantly decrease the expression of p-P70S6K (AKT/mTOR pathway) and p-ERK1/2 (MAPK) proteins. Cell Viability Assay Cell line: Gastric cancer cells (line AGS). Concentration: 10, 25, 50, 100, 200, 400, 800, 1600 and 3200 μg/mL. Incubation time: 1 hour. Result: Cell viability of AGS cells gradually decreased in response to increasing doses of blueberry leaf extract from MeJA treated plants. Western blot analysis. Cell line: AGS cells. Concentration: 10, 50, 100, 200, 400, 800, 1600 and 3200 μg/mL. Incubation time: Result: Blueberry leaf extracts of MeJA-treated plants significantly decreased the expression of p-P70S6K (AKT/mTOR pathway) and p-ERK1/2 (MAPK) proteins.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only