Methyl anthranilate

SKU: orb1297285

Description

Methyl anthranilate is a naturally occurring compound that functions as a novel quorum sensing inhibitor. It demonstrates anti-biofilm activity against Aeromonas sobria in vitro, making it a relevant research tool for studying bacterial communication and infection mechanisms.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 134-20-3
• MW: 151.16
• Purity: 99.96% (May vary between batches)
• Formula: C₈H₉NO₂
• SMILES: COC(=O)C1=CC=CC=C1N
• Target: Antibacterial
• Solubility: DMSO:27.5 mg/mL (181.93 mM)

Bioactivity

• In Vitro:
  0.5 μL/mL of methyl anthranilate evidently reduced biofilm formation (51.44%), swinging motility (74.86%), swarming motility (71.63%), protease activity (43.08%), and acyl-homoserine lactone (AHL) production. Furthermore, the real-time quantitative PCR (RT-qPCR) and in silico analysis showed that methyl anthranilate might inhibit QS system in A. sobria by interfering with the biosynthesis of AHL, as well as competitively binding with receptor protein.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Bacterial, Methyl anthranilate

Compound Identifiers

PubChem CID

8635