Methyl anthranilate

SKU: orb1297285

Description

Methyl anthranilate is a naturally occurring compound that functions as a novel quorum sensing inhibitor. It demonstrates anti-biofilm activity against Aeromonas sobria in vitro, making it a relevant research tool for studying bacterial communication and infection mechanisms.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 134-20-3
• MW: 151.16
• Purity: 99.96% (May vary between batches)
• Formula: C₈H₉NO₂
• SMILES: COC(=O)C1=CC=CC=C1N
• Target: Antibacterial
• Solubility: DMSO:27.5 mg/mL (181.93 mM)

Bioactivity

• In Vitro:
  0.5 μL/mL of methyl anthranilate evidently reduced biofilm formation (51.44%), swinging motility (74.86%), swarming motility (71.63%), protease activity (43.08%), and acyl-homoserine lactone (AHL) production. Furthermore, the real-time quantitative PCR (RT-qPCR) and in silico analysis showed that methyl anthranilate might inhibit QS system in A. sobria by interfering with the biosynthesis of AHL, as well as competitively binding with receptor protein.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Bacterial, Methyl anthranilate

Compound Identifiers

PubChem CID

8635