Methyl Aminolevulinate Hydrochloride

SKU: orb1302259

Description

Methyl aminolevulinate hydrochloride, the methyl ester of 5-aminolevulinic acid, is a prodrug used as a photosensitizer in photodynamic therapy (PDT) research. It is applied in studies investigating PDT for dermatological conditions like acne vulgaris and hypertrophic scarring, utilizing both in vitro and in vivo experimental models.

Research Area

Immunology & Inflammation, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 79416-27-6
• MW: 181.62
• Purity: 99.84%
• Formula: C₆H₁₂ClNO₃
• SMILES: Cl.COC(=O)CCC(=O)CN
• Target: ROS,Others,Reactive Oxygen Species
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (11.01 mM);DMSO:55 mg/mL (302.83 mM)

Bioactivity

• In Vivo:
  In mouse, Spermidine (200 μg) intracerebellar injection (icb), does not alter basal cGMP levels. Spermidine attenuates responses mediated through the NMDA, NMDA-associated glycine receptor and quisqualate receptors. Spermidine is widely distributed in neural and non-neural tissues and has been shown to play a key role in cell differentiation and growth .

Storage & Handling

• Storage: keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, inhibit, Methyl 5-aminolevulinate Hydrochloride, Methyl delta-aminolevulinate Hydrochloride, Methyl aminolevulinate, Methyl Aminolevulinate Hydrochloride, Methyl δ-aminolevulinate hydrochloride, Methyl δ-aminolevulinate Hydrochloride, 5-Aminolevulinic acid methyl ester, carcinoma,?Metvix, Aminolevulinic acid methyl ester Hydrochloride, cell, PDT,?acne, sensitizer, therapy, photosensitiser, photodynamic, Reactive Oxygen Species, vulgaris,?basal

Compound Identifiers

PubChem CID

157921