Methyl 3-O-methylgallate

SKU: orb1309431

Description

Methyl 3-O-methylgallate (M3OMG) is a rare phenolic compound with significant antioxidant properties. It is utilized in biochemical research to study oxidative stress mechanisms, showing potential in both in vitro assays and preliminary in vivo models for related pathologies.

Key Properties

• CAS Number: 3934-86-9
• MW: 198.17
• Purity: 99.93% (May vary between batches)
• Formula: C₉H₁₀O₅
• SMILES: COC(=O)c1cc(O)c(O)c(OC)c1
• Target: Others
• Solubility: DMSO:50 mg/mL (252.31 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (10.09 mM)

Bioactivity

• In Vivo:
  Animals were treated with either Methyl 3-O-methylgallate(10 and 20 mg/kg i.p.), vitamin C (10 mg/kg i.p.) as the standard antioxidant or the vehicle (5 % dimethyl sulfoxide; 1 ml/kg) for 1 week. Oxidative stress was induced in the brain by adding 600 ppm NaF in the drinking water for 7 days. At the end of the treatment period, the levels of thiobarbituric acid reactive substances (TBARS), reduced glutathione and the activities of antioxidant enzymes (superoxide dismutase and catalase) were evaluated in brain homogenates. Methyl 3-O-methylgallate mitigated the NaF-induced oxidative stress through normalization of the level of TBARS, reduced levels of glutathione and by the restoration of the diminished antioxidant enzyme activities.
• In Vitro:
  Methyl 3-O-methylgallate showed antioxidant activity without prooxidant effect in neuronal SH-SY5Y cells.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

M3OMG, Methyl 3Omethylgallate, Methyl 3-O-methylgallate, Methyl 3 O methylgallate, inhibit, Inhibitor

Compound Identifiers

PubChem CID

99622