Methocarbamol

SKU: orb1224773

Description

Methocarbamol is a central muscle relaxant used to treat skeletal muscle spasms.(In Vitro):Methocarbamol (2 mM; for 20 min) significantly increases the decay times of the EPCs and those of the EPPs induced by the phrenic nerve stimulation.Methocarbamol has no effect on Nav1.7 currents.\n(In Vivo):Methocarbamol (200 mg/kg; ip) has Muscle relaxant activity of 88.96%.

Key Properties

• CAS Number: 532-03-6
• MW: 241.24
• Purity: >98% (HPLC)
• Formula: C₁₁H₁₅NO₅
• SMILES: COC1=CC=CC=C1OCC(COC(=O)N)O
• Target: Carbonic Anhydrase
• Solubility: Ethanol: 48 mg/mL (198.97 mM); Water: 2 mg/mL (8.29 mM); DMSO: 48 mg/mL (198.97 mM)

Bioactivity

• In Vivo:
  Methocarbamol (200 mg/kg; ip) has Muscle relaxant activity of 88.96%. Animal model: Mice with weight 20-30 g. Dosage: 200 mg/kg. Administration: IP; single dose. Result: Had Muscle relaxant activity of 88.96%.
• In Vitro:
  Methocarbamol (2 mM; for 20 min) significantly increases the decay times of the EPCs and those of the EPPs induced by the phrenic nerve stimulation. Methocarbamol has no effect on Nav1.7 currents.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

AHR 85 | Guaiacol Glyceryl Ether Carbamate | Guaiphenesin Carbamate | NSC 170960

Quick Database Links

Gene Symbol

Carbonic Anhydrase