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Catalog Number | orb1309433 |
---|---|
Category | Small Molecules |
Description | Metarrestin |
CAS Number | 1443414-10-5 |
Purity | 99.04% |
MW | 474.6 |
SMILES | C(N1C(=C(C2=C1N=CN(C2=N)[C@H]3CC[C@H](O)CC3)C4=CC=CC=C4)C5=CC=CC=C5)C6=CC=CC=C6 |
Formula | C31H30N4O |
Biological Activity | Metarrestin (ML246) is a first-in-class perinucleolar compartment inhibitor with a favorable PK profile, which effectively suppresses metastasis. Metarrestin disrupts the nucleolar structure and inhibits RNA polymerase (Pol) I transcription, at least in part by interacting with the translation elongation factor eEF1A2. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
1443414-10-5 |
[1443414-10-5] | |
474.596107 | |
C31H30N4O |
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