Metahexestrol

SKU: orb3028601

Description

Metahexestrol is an inhibitor of the estrogen receptor (E2R) with antitumor activity. It significantly inhibits the proliferation of estrogen receptor-positive MCF-7 human breast cancer cell line with an ED50 of 1.0 μM. Additionally, Metahexestrol shows inhibitory activity in estrogen receptor-negative MDA-MB-231 cell lines, and its antiproliferative effect is not reversed by estrogen, suggesting that its mechanism may be partially independent of the E2R pathway. Metahexestrol is applicable in research on estrogen-dependent breast cancer.

Research Area

Metabolism Research

Key Properties

• CAS Number: 71953-72-5
• MW: 270.366
• Formula: C₁₈H₂₂O₂
• SMILES: [C@H]([C@H](CC)C1=CC(O)=CC=C1)(CC)C2=CC(O)=CC=C2
• Target: Estrogen Receptor/ERR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Estrogen Receptor/ERR