[Met5,Arg6,Phe7] Enkephalin, amide

SKU: orb2693738

Description

Opioid growth factor (OGF) and its receptor form a biological axis that tonically regulates cell proliferation by delaying the G1/S interface of the cell cycle under homeostatic conditions or in neoplasia. Exogenous OGF represses growth of human pancreatic cancer cells in culture and in nude mice. OGF therapy alone or in combination with standard chemotherapies results in enhanced inhibition of DNA synthesis and tumor growth.

Key Properties

• Target: others
• CAS Number: 78761-61-2
• MW: 876.06
• Purity: ≥95%
• Formula: C₄₂H₅₇N₁₁O₈S
• Protein Sequence: YGGFMRF-NH2

Storage & Handling

• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

others