MET Transcription-IN-1

SKU: orb3135553

Description

MET Transcription-IN-1 (Compound C3) is an orally active inhibitor of MET transcription that efficiently binds to and stabilizes the G-quadruplex in the MET promoter region, thereby inhibiting c-Met expression. It can overcome resistance caused by specific c-Met mutations and effectively inhibits tumor cell proliferation, migration, and invasion, inducing cell cycle arrest and apoptosis. This compound exhibits antitumor activity and is applicable in the study of tumors such as non-small cell lung cancer.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 3082125-66-1
• MW: 392.41
• Formula: C₂₄H₁₆N₄O₂
• SMILES: N1=CC=CC=2C1=C3N=CC=CC3=C4NC(=NC24)C=5OC(=CC5)C=6C=CC=C(OC)C6
• Target: c-Met/HGFR,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

c-Met/HGFR,Apoptosis