Mepazine hydrochloride

• Catalog Number: orb1909004
• Category: Small Molecules
• Description: Mepazine hydrochloride (Pecazine hydrochloride) is a potent MALT1 inhibitor with anticancer and antitumor activities. Mepazine hydrochloride inhibits RANK-induced osteoclastogenesis, suppresses MALT1 activity and tumor growth in pancreatic cancer.
• CAS Number: 2975-36-2
• Purity: 99.76%
• MW: 346.92
• SMILES: Cl.S1C=2C=CC=CC2N(C=3C=CC=CC13)CC4CN(C)CCC4
• Formula: C₁₉H₂₃ClN₂S
• Biological Activity: Mepazine hydrochloride (Pecazine hydrochloride) is a potent and selective inhibitor of the MALT1 protease, with IC50 values of 0.83 μM for GSTMALT1 full length and 0.42 μM for GSTMALT1 325-760. It enhances apoptosis and influences the viability of ABC-DLBCL cells [1].
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.