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Menin-MLL inhibitor 19

SKU: orb3218270

Description

Menin-MLL inhibitor 19 is a small-molecule inhibitor with an exo-aza spiro skeleton that effectively inhibits the interaction between the Menin and MLL (KMT2A) proteins, thereby interfering with the abnormal transcriptional regulation mediated by MLL fusion proteins. It is primarily used to study the mechanisms of the Menin-MLL signaling pathway in diseases such as acute leukemia, myelodysplastic syndrome (MDS), and diabetes.

Images & Validation

Key Properties

CAS Number2360487-93-8
MW645.70
Purity99.97% (May vary between batches)
FormulaC30H34F3N7O4S
SMILESO=C(OC(C)(C)C)N(CC1=CC=C2C(=C1)NC(=O)N2CC(=O)N)C3CCC4(CN(C=5N=CN=C6SC(=CC65)CC(F)(F)F)C4)C3
TargetHistone Methyltransferase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

Available Sizes

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1 mg
$ 340.00
5 mg
$ 760.00
1 ml x 10 mM (in DMSO)
$ 1,030.00