Melflufen

SKU: orb1696158

Description

Melflufen (Melphalan flufenamide) is a dipeptide prodrug of the alkylating agent melphalan. It demonstrates potent antitumor activity against multiple myeloma cells through irreversible DNA damage and anti-angiogenic effects, as shown in in vitro and in vivo studies. The hydrochloride salt form offers improved solubility and stability for research applications.

Research Area

Cell Biology, Molecular Biology

Key Properties

• Target: DNA Alkylator/Crosslinker,Others,Apoptosis
• CAS Number: 380449-51-4
• MW: 498.42
• Formula: C₂₄H₃₀Cl₂FN₃O₃
• SMILES: N(CCCl)(CCCl)C1=CC=C(C[C@@H](C(N[C@@H](CC2=CC=C(F)C=C2)C(OCC)=O)=O)N)C=C1

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

J 1, J1, J-1, Prodrug J-1, Prodrug J-1, Melflufen, Melphalan flufenamide

Compound Identifiers

PubChem CID

9935639