MEK/PI3K-IN-2

SKU: orb1983011

Description

MEK/PI3K-IN-2 (6s) is a dual MEK and PI3K inhibitor with IC50 values of 352 nM (MEK1), 107 nM (PI3Kα), and 137 nM (PI3Kδ). It suppresses pERK1/2 and pAKT signaling, demonstrating anti-proliferative effects in cancer cell lines, which supports its utility for oncology research targeting the MAPK and PI3K pathways.

Research Area

Signal Transduction

Key Properties

• CAS Number: 2281803-33-4
• MW: 957.68
• Formula: C₃₈H₄₁F₅IN₉O₇
• SMILES: OCCN(CCOCCOCCOCCONC(=O)c1ccc(F)c(F)c1Nc1ccc(I)cc1F)c1nc(nc(n1)-n1c(nc2ccccc12)C(F)F)N1CCOCC1
• Target: MEK,ERK,PI3K

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

163408818